I was prescribed Paliperidone at Royal Darwin Hospital.
I noticed that every time I took it, it seemed to kick my heart. So after a few days, I stopped taking it.
Then they started sneaking it into my food at restaurants.
Then my coffee at coffee shops and now into the food on the shelves at the supermarket.
The latest trick is smoke in my face….
Check out the prohibited Drug interactions in magenta below, from Drugs.com, essentially, Garlic, hot weather, exercise, old age, vitamin tablets).
In other words, there is no way known that I should be prescribed this drug by any Doctor that cared for my well being. OK – any Doctor that was actually trying to extend my life – probably wouldn’t prescribe this drug to someone with my high risk profile.
Paliperidone is used for:
Treating schizophrenia. It may also be used for other conditions as determined by your doctor.
Paliperidone is an atypical antipsychotic. Exactly how it works is not known. It is thought to affect certain substances in the brain.
Well drugs.com may not know but the patent [http://www.google.it/patents/US8304431] details quite specifically:
The invention relates to the field of neuropsychiatry. More specifically, the invention relates to the use of compounds, which have D4 and 5-HT2A antagonist, inverse agonist or partial agonist activity
.. and can be used to repair the following psychiatric conditions:
mood, anxiety, perception, feeding, somatic sensations, sexual functions, sleep, cognitive functioning, impulse control, attention, substance use, personality, bereavement, identity, phase of life, abuse or neglect and other aspects of behavior.
Gee, sounds like any Doctor could prescribe this to fix almost any problem that any human might conceivably have…
Or… in 2004, there was a worldwide concerted effort to get the drug approved and listed in all countries because:
It blocks certain perceptive synapse functionality – i.e. the ability of the body to accept Dopamine synaptic updates from it’s neural pathways. (And at further distances away from the brain).
(Interesting explanation at http://web.williams.edu/imput/synapse/pages/IVB5.html)
Or in alternative language to feel the incoming Electro Magnetic Waves and warn the brain to hide under some concrete.
(We covered this in a previous scout report where we said – you cant have human scintillometers telling us the Government is lying… that would be bad form.)
Back to the Drugs,com description….
Do NOT use paliperidone if:
•you are allergic to any ingredient in paliperidone or to risperidone
•you have moderate to severe kidney problems or a history of irregular heartbeat (eg, long QT syndrome, prolonged QT interval)
•you are taking certain antiarrhythmics (eg, amiodarone, procainamide, quinidine, sotalol), certain antipsychotic medicines (eg, chlorpromazine, thioridazine), asenapine, citalopram, metoclopramide, nilotinib, certain quinolone antibiotics (eg, gatifloxacin, moxifloxacin), tetrabenazine, or any other medicine that may increase the risk of a certain type of irregular heartbeat (prolonged QT interval). Check with your doctor or pharmacist if you are unsure if any of your medicines may increase the risk of this type of irregular heartbeat
Before using paliperidone:
Some medical conditions may interact with paliperidone. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
•if you are pregnant, planning to become pregnant, or are breast-feeding
•if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
•if you have allergies to medicines, foods, or other substances
•if you have a history of seizures, heart problems (eg, heart failure; fast, slow, or irregular heartbeat), an abnormal electrocardiogram (ECG), a heart attack, a stroke, transient ischemic attack (TIA) or “mini-stroke,” blood vessel problems, low white blood cell levels, high blood cholesterol or triglyceride levels, or high or low blood pressure
•if you have a history of kidney problems; liver problems; stomach or bowel problems (eg, narrowing, inflammation, blockage); cystic fibrosis; aspiration (inhaling foreign matter into the airway or lungs), including aspiration pneumonia; neuroleptic malignant syndrome (NMS); tardive dyskinesia (TD) (abnormal movements of the tongue or face); suicidal thoughts or attempts; Reye syndrome; alcohol abuse or dependence; or a condition that can cause dizziness or fainting
•if you have diabetes or high blood sugar, or are very overweight, or if a family member has had diabetes
•if you have low blood potassium or magnesium levels, Alzheimer disease, dementia, Parkinson disease, or esophagus problems (eg, trouble swallowing)
•if you have had high blood prolactin levels or a history of certain types of cancer (eg, breast, pancreas, pituitary), or if you are at risk of breast cancer
•if you are dehydrated or have low blood volume, if you drink alcohol, or will be exposed to high temperatures or you exercise strenuously
•if you are taking oral paliperidone or risperidone, or any other antipsychotic medicine
•if you have never taken paliperidone or risperidone
Some MEDICINES MAY INTERACT with paliperidone. Tell your health care provider if you are taking any other medicines, especially any f the following:
•Many prescription and nonprescription medicines (eg, used for allergies, cancer, depression or other mental or mood problems, heartburn, high blood pressure, immune system suppression, irregular heartbeat or other heart problems, malaria or other infections, narcotic or other substance abuse or dependence, nausea or vomiting, pain, Parkinson disease, seizures, sleep problems, Tourette syndrome), multivitamin products, and herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo, St. John’s wort) because they may interact with paliperidone. Ask your doctor or pharmacist if you are unsure if any of your medicines might interact with paliperidone
This may not be a complete list of all interactions that may occur. Ask your health care provider if paliperidone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Paliperidone, the active ingredient in INVEGA® (paliperidone) Extended-Release Tablets, is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives. INVEGA® contains a racemic mixture of (+)- and (-)- paliperidone. The chemical name is (±)-3-[2-[4-(6-fluoro-1,2benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4Hpyrido[1,2-a]pyrimidin-4-one. Its molecular formula is C23H27FN4O3 and its molecular weight is 426.49. The structural formula is:
Paliperidone is sparingly soluble in 0.1N HCl and methylene chloride; practically insoluble in water, 0.1N NaOH, and hexane; and slightly soluble in N,N-dimethylformamide.
INVEGA® (paliperidone) Extended-Release Tablets are available in 1.5 mg (orange-brown), 3 mg (white), 6 mg (beige), and 9 mg (pink) strengths. INVEGA® (paliperidone) utilizes OROS® osmotic drug-release technology.
Inactive ingredients are carnauba wax, cellulose acetate, hydroxyethyl cellulose, propylene glycol, polyethylene glycol, polyethylene oxides, povidone, sodium chloride, stearic acid, butylated hydroxytoluene, hypromellose, titanium dioxide, and iron oxides. The 3 mg tablets also contain lactose monohydrate and triacetin.
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